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Asked: 6 years agoIn:
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corynebacterium
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Corynebacterium is a genus of bacteria that are Gram-positive and most are aerobic. They are bacilli (rod-shaped), and in some phases of life they are, more specifically, club-shaped, which inspired the genus name (coryneform means "club-shaped").

    Corynebacterium is a genus of bacteria that are Gram-positive and most are aerobic. They are bacilli (rod-shaped), and in some phases of life they are, more specifically, club-shaped, which inspired the genus name (coryneform means “club-shaped”).

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Asked: 6 years agoIn: , ,
Nasim
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gram positive bacilli
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test. Gram-positive bacteria take up the crystal violet stain used in the test, and then appear to be purple-coloured when seen through an optical microscope. This is because the thick peptidoglycan laRead more

    In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test.
    Gram-positive bacteria take up the crystal violet stain used in the test, and then appear to be purple-coloured when seen through an optical microscope. This is because the thick peptidoglycan layer in the bacterial cell wall retains the stain after it is washed away from the rest of the sample, in the decolorization stage of the test.

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Asked: 6 years agoIn:
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mycobacterium
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Atypical mycobacteria are mycobacteria that do not cause tuberculosis or leprosy. They are found in nature, such as in soil, water, and animals, and may colonize poorly sanitized medical equipment. They can cause various infections in humans, such as skin, soft tissue, lymph node, lung, and disseminRead more

    Atypical mycobacteria are mycobacteria that do not cause tuberculosis or leprosy. They are found in nature, such as in soil, water, and animals, and may colonize poorly sanitized medical equipment. They can cause various infections in humans, such as skin, soft tissue, lymph node, lung, and disseminated infections. Some of the most common species of atypical mycobacteria that cause human infections are:
    1. Mycobacterium avium complex (MAC)
    2. Mycobacterium kansasii
    3. Mycobacterium marinum
    4. Mycobacterium ulcerans
    5. Mycobacterium abscessus complex
    6. Mycobacterium chelonae, and
    7. Mycobacterium fortuitum

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Asked: 6 years agoIn:
Nasim

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mycobacterium
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Mycobacterium tuberculosis has many virulence factors, which can be divided across: 1. Lipid and fatty acid metabolism, 2. Cell envelope proteins, 3. Macrophage inhibitors, 4. Kinase proteins, 5. Proteases, 6. Metal-transporter proteins, and 7. Gene expression regulators. Some of the virulence factoRead more

    Mycobacterium tuberculosis has many virulence factors, which can be divided across:
    1. Lipid and fatty acid metabolism,
    2. Cell envelope proteins,
    3. Macrophage inhibitors,
    4. Kinase proteins,
    5. Proteases,
    6. Metal-transporter proteins, and
    7. Gene expression regulators.
    Some of the virulence factors of Mycobacterium tuberculosis include:
    1. Surface-exposed lipids in the mycobacterial outer membrane,
    2. Esx family proteins,
    3. Pro-Glu (PE)/ Pro-Pro-Glu (PPE) family proteins secreted by type VII secretion systems (T7SS),
    4. Alternative sigma factors,
    5. Transcriptional repressors and activators,
    6. Two-component signaling systems,
    7. Metabolic enzymes and
    8. Cellular secretory systems.

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Asked: 6 years agoIn: , , ,
Nasim
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diagnosistuberculosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    There are two kinds of tests used to detect TB bacteria in the body: 1. The TB skin test (TST). 2. The TB blood tests. (A positive TB skin test or TB blood test only tells that a person has been infected with TB bacteria. It does not tell whether the person has latent TB infection (LTBI) or has progRead more

    There are two kinds of tests used to detect TB bacteria in the body:
    1. The TB skin test (TST).
    2. The TB blood tests.
    (A positive TB skin test or TB blood test only tells that a person has been infected with TB bacteria. It does not tell whether the person has latent TB infection (LTBI) or has progressed to TB disease.)
    3. Chest x-ray.
    4. Sample of sputum, are needed to see whether the person has TB disease.

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Asked: 6 years agoIn:
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tuberculosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Tuberculosis infection can cause complications such as: Joint damage Lung damage Infection or damage of your bones, spinal cord, brain, or lymph nodes Liver or kidney problems Inflammation of the tissues around your heart

    Tuberculosis infection can cause complications such as:

    Joint damage
    Lung damage
    Infection or damage of your bones, spinal cord, brain, or lymph nodes
    Liver or kidney problems
    Inflammation of the tissues around your heart

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Asked: 6 years agoIn: , , , ,
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clinical featuressymptomstuberculosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Tuberculosis (TB) is a serious illness that mainly affects the lungs. The germs that cause tuberculosis are a type of bacteria. The clinical features of TB can vary depending on the stage of the disease. Here are some common clinical features of active TB disease: - Malaise - Weight loss - Fever - NRead more

    Tuberculosis (TB) is a serious illness that mainly affects the lungs. The germs that cause tuberculosis are a type of bacteria. The clinical features of TB can vary depending on the stage of the disease. Here are some common clinical features of active TB disease:

    – Malaise
    – Weight loss
    – Fever
    – Night sweats
    – Cough
    – Coughing up blood or mucus
    – Chest pain
    – Pain with breathing or coughing
    – Not wanting to eat
    – Tiredness
    – Not feeling well in general

    It’s important to note that these symptoms can also be caused by other illnesses, so it’s important to see a doctor if you are experiencing any of these symptoms.

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Asked: 6 years agoIn: , ,
Nasim
Begginer

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mycobacterium
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Slowly growing Mycobacterium tuberculosis complex (MTBC) members are causative agents of human and animal tuberculosis. Species in this complex include: M. africanum M. bovis M. bovis BCG M. canetti M. caprae M. microti M. mungi M. orygis M. pinnipedii M. suricattae M. tuberculosis, the major causeRead more

    Slowly growing
    Mycobacterium tuberculosis complex (MTBC) members are causative agents of human and animal tuberculosis. Species in this complex include:
    M. africanum
    M. bovis
    M. bovis BCG
    M. canetti
    M. caprae
    M. microti
    M. mungi
    M. orygis
    M. pinnipedii
    M. suricattae
    M. tuberculosis, the major cause of human tuberculosis
    Mycobacterium avium complex
    Mycobacterium avium complex (MAC) is a group of species that, in a disseminated infection but not lung infection, used to be a significant cause of death in AIDS patients. Species in this complex include:
    M. avium
    M. avium paratuberculosis, which has been implicated in Crohn’s disease in humans and is the causative agent of Johne’s disease in cattle and sheep
    M. avium silvaticum
    M. avium “hominissuis”
    M. colombiense
    M. indicus pranii
    M. intracellulare
    Mycobacterium gordonae clade
    M. asiaticum
    M. gordonae
    Mycobacterium kansasii clade
    M. gastri
    M. kansasii
    Mycobacterium nonchromogenicum/terrae clade
    M. hiberniae
    M. icosiumassiliensis
    M. nonchromogenicum
    M. terrae
    M. triviale
    Mycolactone-producing mycobacteria
    M. ulcerans, which causes the “Buruli”, or “Bairnsdale” ulcer
    M. pseudoshottsii
    M. shottsii
    Mycobacterium simiae clade
    M. florentinum
    M. genavense
    M. heidelbergense
    M. interjectum
    M. kubicae
    M. lentiflavum
    M. montefiorense
    M. palustre
    M. parascrofulaceum
    M. simiae
    M. triplex
    Ungrouped
    M. arabiense
    M. aromaticivorans
    M. aquaticum
    M. bacteremicum
    M. bohemicum
    M. botniense
    M. branderi
    M. celatum
    M. chimaera
    M. conspicuum
    M. cookii
    M. doricum
    M. farcinogenes
    M. haemophilum
    M. heckeshornense
    M. intracellulare
    M. lacus
    M. leprae, which causes leprosy
    M. lepraemurium
    M. lepromatosis, another (less significant) cause of leprosy, described in 2008
    M. liflandii
    M. llatzerense
    M. malmoense
    M. marinum, causes a rare disease called Aquarium granuloma.
    M. neoaurum
    M. monacense
    M. murale
    M. nebraskense
    M. saskatchewanense
    M. sediminis
    M. scrofulaceum
    M. shimoidei
    M. szulgai
    Mycobacterium talmoniae
    M. tusciae
    M. xenopi
    M. yongonense
    Intermediate growth rate
    M. intermedium
    Rapidly growing
    Mycobacterium abscessus clade
    M. abscessus
    M. bolletii
    M. massiliense
    Together they are known as the M. abscessus complex

    Mycobacterium chelonae clade
    M. chelonae
    M. immunogenum
    M. stephanolepidis
    Mycobacterium fortuitum clade
    M. boenickei
    M. brisbanense
    M. cosmeticum
    M. fortuitum
    M. fortuitum subsp. acetamidolyticum
    M. houstonense
    M. mageritense
    M. neworleansense
    M. peregrinum
    M. porcinum
    M. senegalense
    M. septicum
    Mycobacterium mucogenicum clade
    Mycobacterium aubagnese
    M. mucogenicum
    Mycobacterium phocaicum
    Mycobacterium parafortuitum clade
    M. austroafricanum
    M. diernhoferi
    M. frederiksbergense
    M. hodleri
    M. neoaurum
    M. parafortuitum
    Mycobacterium vaccae clade
    M. aurum
    M. vaccae
    CF (Cystic Fibrosis)
    M. chitae
    M. fallax
    Ungrouped
    M. agri
    M. aichiense
    M. alvei
    M. arupense
    M. barrassiae
    M. brumae
    M. canariasense
    M. chubuense
    M. conceptionense
    M. confluentis
    M. duvalii
    M. elephantis
    M. flavescens
    M. gadium
    M. gilvum
    M. hassiacum
    M. holsaticum
    M. iranicum
    M. komossense
    M. madagascariense
    M. massilipolynesiensis
    M. moriokaense
    M. obuense
    M. phlei
    M. psychrotolerans
    M. pulveris
    M. pyrenivorans
    M. smegmatis
    M. goodii
    M. wolinskyi
    M. sphagni
    M. thermoresistibile
    M. vanbaalenii
    Ungrouped
    M. arosiense
    M. aubagnense
    M. chlorophenolicum
    M. fluoroanthenivorans
    M. kumamotonense
    M. novocastrense
    M. parmense
    M. poriferae
    M. rhodesiae
    M. seoulense
    M. tokaiense

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Asked: 6 years agoIn:
Nasim

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mycobacterium
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Mycobacterium is a genus of Actinomycetota, given its own family, the Mycobacteriaceae. Over 190 species are recognized in this genus. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (Mycobacterium tuberculosis) and leprosy (Mycobacterium leprae) in hRead more

    Mycobacterium is a genus of Actinomycetota, given its own family, the Mycobacteriaceae. Over 190 species are recognized in this genus. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (Mycobacterium tuberculosis) and leprosy (Mycobacterium leprae) in humans. The Greek prefix myco- means ‘fungus’, alluding to the way mycobacteria have been observed to grow in a mold-like fashion on the surface of cultures. It is acid-fast and cannot be stained by the Gram stain procedure.
    Mycobacteria are Gram-positive, catalase positive, non-motile, non-spore forming rod-shaped bacteria (0.2–0.6 μm wide and 1.0–10 μm long). The colony morphology of mycobacteria varies with some species growing as rough or smooth colonies. Colony colour ranges from white to orange or pink (Iivanainen, 1999). Most mycobacteria are aerobic organisms, although some species are microaerophilc (Falkinham, 1996).

    The cell walls of mycobacteria are very thick and consist of four layers. The innermost layer is composed of peptidoglycan and the others of lipids. The presence of lipid provides the bacteria with resistance to acid and alkaline environments and renders the cells relatively impermeable to various basic dyes, which need to be combined with phenol to allow penetration of the cell wall. The cell wall composition renders mycobacteria hydrophobic, and as a result these bacteria tend to grow in aggregates that ‘float’ on the surface of liquid media. Detergents, such as Tween® 80 can be added to culture media to disperse the organisms. Certain mycobacteria, including Mycobacterium paratuberculosis (MAP), can shed their cell walls, forming spheroplasts which are not detected using the acid-fast stain test (Hines and Styer, 2003).

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Asked: 6 years agoIn: , , ,
Nasim

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choleravibrio cholerae
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    This answer was edited.

    Stool culture — A definitive diagnosis of cholera is based on isolation of the organism from clinical samples, which also permits a determination of the antibiotic susceptibility profile. V. cholerae can be isolated from stool using selective media such as thiosulfate citrate bile sucrose agar or taRead more

    Stool culture — A definitive diagnosis of cholera is based on isolation of the organism from clinical samples, which also permits a determination of the antibiotic susceptibility profile. V. cholerae can be isolated from stool using selective media such as thiosulfate citrate bile sucrose agar or taurocholate tellurite gelatin agar. Once cultured, V. cholerae can be identified by biochemical tests; serogroup and serotype can be assigned by testing with specific antibodies. In settings such as the United States, where cholera is a sporadic illness, the clinical microbiology laboratory should be informed of a suspicion of cholera so that appropriate selective media can be used. These selective media are not routinely used for stool culture.

    The recovery of viable V. cholerae from clinical specimens can be enhanced by enrichment in alkaline peptone water . V. cholerae can also persist in a number of standard transport media, including Cary-Blair media, while being transported to a central laboratory from field settings.

    Rapid tests and other tools

    ●Antigen detection − Several rapid antigen detection-based tests are commercially available for diagnosis of cholera. These include immunochromatographic lateral flow devices (dipsticks), such as Crystal VC, which detect the presence of the O1 or O139 antigen in watery diarrheal stools, and Cholkit, which detects only the O1 antigen. In one meta-analysis including 20 studies representing 8 different commercial rapid tests, the combined sensitivity was 90 percent (95% CI 86-93) and the specificity was 86 percent (95% CI 81-90), relative to bacterial culture (the diagnostic gold standard); there was variation across individual studies.

    The sensitivity of culture is diminished among individuals who no longer shed viable bacteria in the stool; negative stool culture may be observed in the setting of antibiotic administration and/or coinfection with lytic bacteriophage. The apparent diminished specificity of antigen-based dipstick tests (bacterial culture used as the diagnostic gold standard) may reflect of the limits of bacterial culture. To account for this, one study evaluated the performance of Cholkit, Crystal VC, microbial culture, and polymerase chain reaction (PCR) using a Bayesian latent class modeling approach; the sensitivity of Cholkit and Crystal VC were 98 percent (95% CI 88-100 percent for both), with specificities of 97 percent (95% CI 89-100 percent) and 98 percent (95% CI 92-100 percent), respectively.

    ●Molecular tests − Molecular testing for V. cholerae (eg, PCR), including tests that use dried fecal spots, is also feasible; however, thus far practical use of molecular tests has been limited to epidemiologic research and surveillance.

    ●Darkfield microscopy − Darkfield microscopy of rice-water stools (at 400x magnification) can also be used to evaluate for the presence of highly motile Vibrios, whose shooting star-like motion can be inhibited by the subsequent addition of specific antibodies [52]. Darkfield microscopy is quite specific for V. cholerae but lacks sufficient sensitivity to be used reliably for diagnosis.

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