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Atypical mycobacteria are mycobacteria that do not cause tuberculosis or leprosy. They are found in nature, such as in soil, water, and animals, and may colonize poorly sanitized medical equipment. They can cause various infections in humans, such as skin, soft tissue, lymph node, lung, and disseminRead more
Atypical mycobacteria are mycobacteria that do not cause tuberculosis or leprosy. They are found in nature, such as in soil, water, and animals, and may colonize poorly sanitized medical equipment. They can cause various infections in humans, such as skin, soft tissue, lymph node, lung, and disseminated infections. Some of the most common species of atypical mycobacteria that cause human infections are:
1. Mycobacterium avium complex (MAC)
2. Mycobacterium kansasii
3. Mycobacterium marinum
4. Mycobacterium ulcerans
5. Mycobacterium abscessus complex
6. Mycobacterium chelonae, and
7. Mycobacterium fortuitum
Mycobacterium tuberculosis has many virulence factors, which can be divided across: 1. Lipid and fatty acid metabolism, 2. Cell envelope proteins, 3. Macrophage inhibitors, 4. Kinase proteins, 5. Proteases, 6. Metal-transporter proteins, and 7. Gene expression regulators. Some of the virulence factoRead more
Mycobacterium tuberculosis has many virulence factors, which can be divided across:
See less1. Lipid and fatty acid metabolism,
2. Cell envelope proteins,
3. Macrophage inhibitors,
4. Kinase proteins,
5. Proteases,
6. Metal-transporter proteins, and
7. Gene expression regulators.
Some of the virulence factors of Mycobacterium tuberculosis include:
1. Surface-exposed lipids in the mycobacterial outer membrane,
2. Esx family proteins,
3. Pro-Glu (PE)/ Pro-Pro-Glu (PPE) family proteins secreted by type VII secretion systems (T7SS),
4. Alternative sigma factors,
5. Transcriptional repressors and activators,
6. Two-component signaling systems,
7. Metabolic enzymes and
8. Cellular secretory systems.