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The pathogenesis of Vibrio cholerae is as follows: The infection due to V. cholera is acquired due to the ingestion of contaminated food and drinks. Vibrio are highly susceptible to acids and gastric acidity provides an effective barrier against small doses of cholera vibrios. Once the bacteria reacRead more
The pathogenesis of Vibrio cholerae is as follows: The infection due to V. cholera is acquired due to the ingestion of contaminated food and drinks. Vibrio are highly susceptible to acids and gastric acidity provides an effective barrier against small doses of cholera vibrios. Once the bacteria reach the small intestine, they multiply and produce cholera toxin. The toxin causes the cells lining the small intestine to secrete large amounts of water and electrolytes into the lumen of the intestine, leading to profuse watery diarrhea.
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