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Transformation of one differentiated cell type to another differentiated cell type. The change from one type of cell to another may be part of a normal maturation process or caused by some sort of abnormal stimulus. Today, metaplastic changes are usually considered to be an early phase of carcinogenRead more
Transformation of one differentiated cell type to another differentiated cell type. The change from one type of cell to another may be part of a normal maturation process or caused by some sort of abnormal stimulus.
See lessToday, metaplastic changes are usually considered to be an early phase of carcinogenesis, specifically for those with a history of cancers or who are known to be susceptible to carcinogenic changes. Metaplastic change is thus often viewed as a premalignant condition that requires immediate intervention, either surgical or medical, lest it leads to cancer via malignant transformation.