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Uremia can cause serious complications if it’s not treated. Your body may accumulate excess acid, or hormone and electrolyte imbalances –especially for potassium – that can affect the heart. These problems can affect your metabolism, or your body’s process of converting food to energy. The buildup of toxins in your blood can also cause blood vessels to calcify (harden). Calcification leads to bone, muscle, and heart and blood vessel problems. Other complications of uremia may include:
1. Acidosis (too much acid in your blood).
2. Anemia (too few healthy red blood cells).
3. High blood pressure.
4. Hyperkalemia (too much potassium in your blood).
5. Hyperparathyroidism (too much calcium and phosphorus in your blood leading to elevated parathyroid hormone levels and bone abnormalities).
6. Hypothyroidism (underactive thyroid).
7. Infertility (inability to get pregnant).
8. Malnutrition (lack of nutrients in your body).
9. Pulmonary edema (fluid in your lungs).
10. Defective platelet function and blood clotting leading to bleeding
11. Uremic encephalopathy (decreased brain function due to toxin buildup).
12. Angina (chest pain).
13. Atherosclerosis (hardened arteries).
14. Heart failure.
15. Heart valve disease.
16. Pericardial effusion (fluid around your heart).
17. Stroke.