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Bacteria called group A streptococcus (GAS) causes common infections such as strep throat and skin infections. GAS produces a toxic enzyme known as streptolysin O. Your immune system produces antibodies to fight this toxic enzyme. One of these antibodies is called antistreptolysin O (ASO).
An antistreptolysin O titer measures how much ASO is in your blood. The ASO antibodies start increasing about a week after you experience a strep infection.