What is Albuminous urine?
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Albuminous urine (albuminuria or proteinuria) means that albumin—a plasma protein normally retained by healthy kidneys—appears in the urine. In a healthy individual, the glomerular filter blocks virtually all albumin, so urine albumin excretion is 300 mg albumin/day (uACR >300 mg/g)—indicates morRead more
Albuminous urine (albuminuria or proteinuria) means that albumin—a plasma protein normally retained by healthy kidneys—appears in the urine. In a healthy individual, the glomerular filter blocks virtually all albumin, so urine albumin excretion is 300 mg albumin/day (uACR >300 mg/g)—indicates more advanced glomerular damage.
Detection is by a urine dipstick (qualitative) followed by quantitative measurement of albumin-to-creatinine ratio (uACR) or 24-hour urine collection.
Clinically, albuminuria:
See less• Often asymptomatic—foamy urine and peripheral edema may occur as levels rise.
• Serves as both a marker of kidney disease progression and an independent risk factor for cardiovascular events.
• Guides therapy—ACE inhibitors or ARBs are first-line to reduce albuminuria and slow kidney damage.