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Diphtheria is caused by bacteria that adhere to the lining of your respiratory system and generate a toxin that damages your respiratory tissue cells. The pathogenesis of diphtheria is based upon two primary determinants: the ability of a given strain of C diphtheria to colonize in the nasopharyngeaRead more
Diphtheria is caused by bacteria that adhere to the lining of your respiratory system and generate a toxin that damages your respiratory tissue cells. The pathogenesis of diphtheria is based upon two primary determinants: the ability of a given strain of C diphtheria to colonize in the nasopharyngeal cavity and/or on the skin, and its ability to produce diphtheria toxin. The organism produces a toxin that inhibits cellular protein synthesis and is responsible for local tissue destruction and formation of the pseudomembrane that is characteristic of this disease.
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