What are the cultural characteristics of streptococcus pyogenes?
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Streptococcus pyogenes is an aerobe and facultative anaerobe that grows best at an optimum temperature of 37°C and an optimum pH of 7.2. It requires enriched media for growth, such as blood agar, where it produces small (0.5-1mm), circular, semi-transparent colonies that produce a wide zone of β-hemolysis. Growth and hemolysis are promoted by 5-10% CO2. Virulent strains, on fresh isolation form lesions, and produce a ‘matt’ (finely granular) colony while avirulent strains form ‘glossy’ colonies.