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Reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune system and these reactions may be damaging, uncomfortable, or occasionally fatal. Hypersensitivity reactions require a pre-sensitized (immune) state ofRead more
Reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune system and these reactions may be damaging, uncomfortable, or occasionally fatal. Hypersensitivity reactions require a pre-sensitized (immune) state of the host. The Gell and Coombs classification of hypersensitivity is the most widely used and distinguishes four types of immune response that result in bystander tissue damage.
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Hypersensitivity refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an overreaction of the immune system and these reactions may be damaging and uncomfortable. Hypersensitivity reactions can be classified into fRead more
Hypersensitivity refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an overreaction of the immune system and these reactions may be damaging and uncomfortable.
Hypersensitivity reactions can be classified into four types:
See less– **Type I:** IgE mediated immediate reaction
– **Type II:** Antibody-mediated reaction (IgG or IgM antibodies)
– **Type III:** Immune complex-mediated reaction
– **Type IV:** Cytotoxic, cell-mediated, delayed hypersensitivity reaction