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Asked: 6 years agoIn:
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necrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Necrosis is the death of cells in your body tissues. When the cells in your tissues die, it can affect many different areas of your body, including your bones, skin, and organs. Some complications of necrosis include leakage and skin irritations, high output resulting in fluid and electrolyte imbalaRead more

    Necrosis is the death of cells in your body tissues. When the cells in your tissues die, it can affect many different areas of your body, including your bones, skin, and organs. Some complications of necrosis include leakage and skin irritations, high output resulting in fluid and electrolyte imbalances, or stoma necrosis; late complications include parastomal hernia, stoma prolapse, and stoma stenosis. In the case of avascular necrosis (AVN), when the bone does not get enough oxygen, the bone tissue can die. When there is not enough blood reaching the bone, the joint can narrow and the bone can collapse.

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Asked: 6 years agoIn: ,
Nasim

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degenerationdifferencenecrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Cell degeneration: Degenerative definition is a pathological condition that causes cells to change in structure and function. Injury is mainly in the cytoplasm of the cell. These lesions are reversible when the pathological stimuli are reduced or eliminated. There are 3 basic types of degeneration:Read more

    Cell degeneration: Degenerative definition is a pathological condition that causes cells to change in structure and function. Injury is mainly in the cytoplasm of the cell. These lesions are reversible when the pathological stimuli are reduced or eliminated. There are 3 basic types of degeneration:
    Granular Degeneration: : is a pathological condition in which the cells are enlarged with water, and small granules appear in the cytoplasm of the cells, which become red when stained with hematoxylin-eosin. (H.E.). The functional activity of degenerative cells is reduced. This is a non-specific lesion, common in the parenchymal cells of the viscera (hepatocytes in heart failure, renal tubular cells in toxicity).
    Hydropic degeneration : Closely related to granulomatous degeneration. Cells swell, water accumulates in the endoplasmic reticulum sacs, forming unequal light cavities. Dehydration is common in visceral parenchymal cells (liver cells, renal tubular cells) due to lack of oxygen or toxicity. Lipoic degeneration: A condition in which fat droplets appear in the cytoplasm of cells. Fat degeneration is manifested by large, round, light cavities in the cytoplasm of cells when stained with H.E… Fatty degeneration is common in hepatocytes, especially in the central lobules, due to metabolic disorders. alcoholism, after hepatitis).

    Cell necrosis: Definition: Necrosis is the death of cells and tissues that occurs in a living organism. There are 5 main types of cell necrosis:
    Coagulative necrosis: The necrotic tissue has solidification of intracellular and extracellular fluids, the necrotic tissue becomes solid, yellow-gray in color. Coagulation necrosis is common in the extremities and fingers and is often caused by vascular disease (arteritis embolism). Coagulation necrosis is also common in solid organs such as the heart and liver (myocardial infarction). Liquefactive necrosis: The necrotic tissue is liquefied, soft, in the necrotic tissue or with bacterial invasion and many inflammatory cells. Water necrosis is seen in cerebral infarction (cerebral infarction): the brain cells lose shape, liquefy, the brain becomes soft and eventually becomes a fluid-filled cyst. Water necrosis is also seen in myocardial infarction when there is an infection. Caseous necrosis: The necrotic tissue is yellowish-white, friable, and fragile (resembling bean paste). Podiatric necrosis is common in pulmonary tuberculosis and lymphadenopathy. The fovea of ​​necrosis in tuberculosis is called pox necrosis. Podiatric necrosis can also be seen in fungal diseases (histoplasmosis). Fat necrosis: The area of ​​necrosis is white like a candle because the active lipolytic enzymes convert fat into glycerol and free fatty acids. Fat necrosis in acute pancreatitis: the pancreas is swollen, the pancreatic duct is blocked, the pancreatic juice destroys the pancreatic tissue and the fatty tissue around the pancreas, forming candles in the abdomen. Fibrinoid necrosis: The area of ​​necrosis forms a pinkish (eosin-stained) substance resembling fibrin. Fibrous necrosis is common on the serosa surface (inflammation of the pleura, pericardium, and fibrin peritoneum). The surface of the inflamed necrotic membrane is rough or sticky (adhesions to the pleura, pericardium, and peritoneum).

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Asked: 6 years agoIn: ,
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morphologynecrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Morphology of necrotic cell: A) Cytoplasmic changes: -Increased eosinophilia – Due to denatured proteins and loss of cytoplasmic RNA. -Glassy homogenous appearance – loss of glycogen particles. -Moth eaten appearance of cytoplasm – enzymatic digestion of cytoplasmic organelles. -Whorled phospholipidRead more

    Morphology of necrotic cell:

    A) Cytoplasmic changes:
    -Increased eosinophilia – Due to denatured proteins and loss of cytoplasmic RNA.
    -Glassy homogenous appearance – loss of glycogen particles.
    -Moth eaten appearance of cytoplasm – enzymatic digestion of cytoplasmic organelles.
    -Whorled phospholipid masses derived from damaged cell membranes – myelin figures.
    -Calcifications – fatty acids derived from phospholipid masses.

    B) Electron microscopic findings: Necrotic cells are characterized by-
    -Discontinuities in plasma and organellar membrane.
    -Swollen mitochondria with large amorphous densities.
    -Intracytoplasmic myelin figures.
    -Aggregates of fluffy material representing denatured proteins.

    C) Nuclear changes: Due to the non-specific breakdown of DNA, 3 patterns are identified-
    -Karyolysis – fading of basophilia of chromatin due to enzymatic degradation of DNA by endonucleases.
    -Pyknosis – nuclear shrinkage & increased basophilia.
    -Karyorrhexis – pyknotic nucleus undergoes fragmentation.

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Asked: 6 years agoIn:
Nasim

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necrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    **Coagulative necrosis** generally occurs due to an infarct (lack of blood flow from an obstruction causing ischemia) and can occur in all the cells of the body except the brain. The heart, kidney, adrenal glands, or spleen are good examples of coagulative necrosis. Cells that undergo coagulative neRead more

    **Coagulative necrosis** generally occurs due to an infarct (lack of blood flow from an obstruction causing ischemia) and can occur in all the cells of the body except the brain. The heart, kidney, adrenal glands, or spleen are good examples of coagulative necrosis. Cells that undergo coagulative necrosis can become dry, hard, and white.

    On the other hand, **caseous necrosis** is a unique form of cell death in which the tissue maintains a cheese-like appearance. It is also a distinctive form of coagulative necrosis. The dead tissue appears as a soft and white proteinaceous dead cell mass. Frequently, caseous necrosis is encountered in the foci of tuberculosis infections.

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Asked: 6 years agoIn: ,
Nasim

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apoptosisdifferencenecrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Apoptosis and necrosis are both ways cells die. Apoptosis is the normal, healthy way cells die. They die naturally to maintain cellular balance in your body. Apoptosis is needed for your body to function normally. Apoptosis very rarely needs treatment. Cells die through necrosis accidentally due toRead more

    Apoptosis and necrosis are both ways cells die. Apoptosis is the normal, healthy way cells die. They die naturally to maintain cellular balance in your body. Apoptosis is needed for your body to function normally. Apoptosis very rarely needs treatment.

    Cells die through necrosis accidentally due to internal or external factors. These factors may include diseases, infections, injuries, or other conditions. These conditions lead to damage in your cell walls, which makes them unable to function normally. Necrosis generally needs treatment.

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Asked: 6 years agoIn:
Nasim

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necrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Necrosis is the death of cells in your body tissues. It can occur due to injuries, infections, diseases, lack of blood flow to your tissues, and extreme environmental conditions. Some common causes of necrosis include spider bites, gangrene, bed sores, necrotizing fasciitis, osteonecrosis, frostbiteRead more

    Necrosis is the death of cells in your body tissues. It can occur due to injuries, infections, diseases, lack of blood flow to your tissues, and extreme environmental conditions. Some common causes of necrosis include spider bites, gangrene, bed sores, necrotizing fasciitis, osteonecrosis, frostbite, and avascular necrosis.

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Asked: 6 years agoIn:
Nasim

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necrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    When your body’s cells die of necrosis, they form different patterns and appearances. The dead cells appear one of six ways. These patterns include: 1. Coagulative necrosis- With coagulative necrosis, the dead cells remain firm and look normal for days after death. Lack of blood flow or oxygen to anRead more

    When your body’s cells die of necrosis, they form different patterns and appearances. The dead cells appear one of six ways. These patterns include:

    1. Coagulative necrosis-
    With coagulative necrosis, the dead cells remain firm and look normal for days after death. Lack of blood flow or oxygen to any part of your body except your brain can cause coagulative necrosis.

    2. Liquefactive necrosis-
    With liquefactive necrosis, the dead cells partially or completely dissolve within hours of death. Then they transform into a thick, sticky liquid. The cells sometimes appear creamy yellow because pus is forming. Infections and lack of oxygen to your brain can cause liquefactive necrosis.

    3. Fat necrosis-
    With fat necrosis, damaged cells release enzymes, causing them to turn to liquid. The liquid cells combine with calcium, creating chalky, white deposits on the cells. Acute pancreatitis is the most common cause of fat necrosis. It can also occur in breast tissue.

    4. Caseous necrosis-
    With caseous necrosis, the dead cells look white and soft. They’ve been described as looking like cheese — the word caseous means “cheese-like.” Caseous necrosis is uniquely seen in the infectious lung disease tuberculosis.

    5. Fibrinoid necrosis-
    With fibrinoid necrosis, the dead cells appear pink and lack structure. This is because plasma proteins (fibrins) are leaking out of your blood vessel walls. Fibrinoid necrosis occurs when an autoimmune disease or infection damage your blood vessels.

    6. Gangrenous necrosis-
    With gangrenous necrosis, your skin appears black and is beginning to rot. Lack of blood flow to your legs can cause gangrenous necrosis. It can sometimes affect your arms and fingers too.

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Asked: 6 years agoIn:
Nasim

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.

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necrosis
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    Necrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed. When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.

    Necrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed. When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.

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Asked: 6 years agoIn:
Nasim

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cell injury
  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala

    There are four types of cell injury: 1. Necrosis, 2. Apoptosis, 3. Autophagy, and 4. Necrosis with apoptosis. Cell injury can be: 1. Reversible or 2. Irreversible, and can be caused by mechanisms such as mitochondrial damage, abnormal calcium homeostasis, DNA damage, membrane damage, endoplasmic retRead more

    There are four types of cell injury:
    1. Necrosis,
    2. Apoptosis,
    3. Autophagy, and
    4. Necrosis with apoptosis.
    Cell injury can be:
    1. Reversible or
    2. Irreversible, and can be caused by mechanisms such as mitochondrial damage, abnormal calcium homeostasis, DNA damage, membrane damage, endoplasmic reticulum (ER) stress, and oxidative stress. Cell death is a state in which the cell ceases to carry out functions.

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