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mdpathyqa Latest Questions

Asked: 6 years agoIn: Pathology

What is the pathophysiology of embolism?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 3 years ago

    An embolism is the obstruction of the flow of blood by an embolus, a particle or aggregate of substance that is abnormally present in the bloodstream. When a thrombus, a blood clot, becomes dislodged and a piece breaks off, it is called an embolus. The embolus can obstruct the pulmonary circulation,Read more

    An embolism is the obstruction of the flow of blood by an embolus, a particle or aggregate of substance that is abnormally present in the bloodstream. When a thrombus, a blood clot, becomes dislodged and a piece breaks off, it is called an embolus. The embolus can obstruct the pulmonary circulation, and the body sends a signal to release neurohormonal substances and inflammatory mediators, which cause vasoconstriction.

    Pulmonary embolism occurs when clots break off and embolize into the pulmonary circulation. Pulmonary emboli are typically multiple, with the lower lobes being involved more frequently than the upper, and bilateral lung involvement being more common. Once deep venous thrombosis develops, clots may dislodge and travel through the venous system and the right side of the heart to lodge in the pulmonary arteries, where they partially or completely occlude one or more vessels.

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Asked: 6 years agoIn: Pathology

What are the classification of embolism?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 4 years ago

    There are different types of embolism classified based on the embolic material: 1. Thromboembolism - embolism of thrombus or blood clot. 2. Fat embolism - embolism of fat droplets. 3. Air embolism (also known as a gas embolism) - embolism of air bubbles. 4. Septic embolism - embolism of pus containiRead more

    There are different types of embolism classified based on the embolic material:

    1. Thromboembolism – embolism of thrombus or blood clot.

    2. Fat embolism – embolism of fat droplets.

    3. Air embolism (also known as a gas embolism) – embolism of air bubbles.

    4. Septic embolism – embolism of pus containing bacteria.

    5. Tissue embolism – embolism of small fragments of tissue.

    6. Foreign body embolism – embolism of foreign materials such as talc and other small objects.

    7. Amniotic fluid embolism – embolism of amniotic fluid, fetal cells, hair or other debris that enter the mother’s blood stream via the placental bed of the uterus and trigger an allergic reaction.

    The pathway of the embolus can have 3 different types:

    1. Anterograde.
    2. Retrograde.
    3. Paradoxical.
    In anterograde embolism, we say that the movement of emboli is according to the direction of blood flow. However it is otherwise in retreograde embolism, when the weight of the emboli is high enough to oppose the blood flow direction. This is usually only siginificant in blood vessels with low pressure (veins) or emboli of high weight. In paradoxical embolism or also known as crossed embolism, the embolus from veins are crossed to the arterial blood system. This is usually only found in heart defects such as septal defects between the atria or ventricles.

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Asked: 6 years agoIn: Pathology

Define embolism?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 4 years ago

    An embolism is a blocked artery caused by a foreign body, such as a blood clot or an air bubble.

    An embolism is a blocked artery caused by a foreign body, such as a blood clot or an air bubble.

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Asked: 6 years agoIn: Pathology

How angiogenesis occurs?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 3 years ago

    Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels. This process involves the migration, growth, and differentiation of endothelial cells, which line the inside wall of blood vessels. The process of angiogenesis is controlled by chemical signalsRead more

    Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels. This process involves the migration, growth, and differentiation of endothelial cells, which line the inside wall of blood vessels. The process of angiogenesis is controlled by chemical signals in the body, such as vascular endothelial growth factor (VEGF), which is a proangiogenic growth factor. Angiogenesis continues the growth of the vasculature mainly by processes of sprouting and splitting.

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Asked: 6 years agoIn: Pathology

What is angiogenesis?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 4 years ago

    Angiogenesis is the process of new capillaries forming out of preexisting blood vessels in your body. It’s normally a helpful, important process that supports wound healing and supplies oxygen-rich blood to your organs and tissues. But in people with cancer, angiogenesis supports tumor growth and spRead more

    Angiogenesis is the process of new capillaries forming out of preexisting blood vessels in your body. It’s normally a helpful, important process that supports wound healing and supplies oxygen-rich blood to your organs and tissues. But in people with cancer, angiogenesis supports tumor growth and spread by feeding tumors with oxygen and nutrients.

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Asked: 6 years agoIn: Pathology

What are the sequence of events in secondary wound healing?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 3 years ago

    Secondary wound healing occurs when the sides of the wound are not opposed, therefore healing must occur from the bottom of the wound upwards. It occurs in the same four stages as primary intention: Haemostasis, Inflammation, Proliferation, and Remodelling. In Haemostasis, a large fibrin mesh forms,Read more

    Secondary wound healing occurs when the sides of the wound are not opposed, therefore healing must occur from the bottom of the wound upwards. It occurs in the same four stages as primary intention: Haemostasis, Inflammation, Proliferation, and Remodelling. In Haemostasis, a large fibrin mesh forms, which fills the wound. In Inflammation, an inflammatory response acts to remove any cell debris and pathogens present. In Proliferation, cytokines released by inflammatory cells drive the proliferation of fibroblasts and the formation of granulation tissue. Angiogenesis is promoted by the presence of growth mediators, allowing for further maturation of the granulation tissue; the production of collagen by fibroblasts allows for the closure of the wound after around a week. In Remodelling, collagen fibres are deposited within the wound to provide strength in the region, with the fibroblasts subsequently undergoing apoptosis.

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Asked: 6 years agoIn: Pathology

What are the sequence of events in primary wound healing?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 3 years ago

    Primary wound healing, or primary intention wound healing, occurs in wounds with dermal edges that are close together. It is usually faster than secondary intention and occurs in four stages: Haemostasis, Inflammation, Proliferation, and Remodelling. In Haemostasis, the action of platelets and cytokRead more

    Primary wound healing, or primary intention wound healing, occurs in wounds with dermal edges that are close together. It is usually faster than secondary intention and occurs in four stages: Haemostasis, Inflammation, Proliferation, and Remodelling. In Haemostasis, the action of platelets and cytokines forms a hematoma and causes vasoconstriction, limiting blood loss in the affected area. The close proximity of the wound edges allows for ease of clot formation and prevents infection by forming a scab. In Inflammation, a cellular inflammatory response acts to remove any cell debris and pathogens present. In Proliferation, cytokines released by inflammatory cells drive the proliferation of fibroblasts and the formation of granulation tissue. Angiogenesis is promoted by the presence of growth mediators, allowing for further maturation of the granulation tissue; the production of collagen by fibroblasts allows for the closure of the wound after around a week. In Remodelling, collagen fibers are deposited within the wound to provide strength in the region, with the fibroblasts subsequently undergoing apoptosis.

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Asked: 6 years agoIn: Pathology

What are the differences between primary and secondary wound healing?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 3 years ago

    Primary and secondary wound healing differ in the way the wound is closed and the time it takes for the wound to heal. Primary wound healing, or primary intention wound healing, occurs in wounds with dermal edges that are close together. The wound is closed using staples, stitches, glues, or other fRead more

    Primary and secondary wound healing differ in the way the wound is closed and the time it takes for the wound to heal. Primary wound healing, or primary intention wound healing, occurs in wounds with dermal edges that are close together. The wound is closed using staples, stitches, glues, or other forms of wound-closing processes. This reduces the tissue lost and allows the body to focus on closing and healing a smaller-area wound rather than the larger initial wound. It is usually faster than secondary intention.

    Secondary wound healing, or secondary intention wound healing, occurs when a wound that cannot be stitched causes a large amount of tissue loss. Doctors will leave the wound to heal naturally in these cases. This may be more common for wounds that have a rounder edge, cover uneven surfaces, or are on surfaces of the body where movement makes stitches or other closure methods impossible. Secondary wound healing relies on the body’s own healing mechanisms. This process takes longer, which may be due to increased wound size, the risk of infection and contamination, and other factors.

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Asked: 6 years agoIn: Pathology

What are the complications of wound healing?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 4 years ago

    Specific Wound Healing Complications and Interventions: 1. Infection. The most common cause of delayed healing in chronic wounds is infection. 2. Osteomyelitis. 3. Tissue Necrosis and Gangrene. 4. Periwound Dermatitis. 5. Edema and Periwound Edema. 6. Hematomas. 7. Dehiscence.

    Specific Wound Healing Complications and Interventions:
    1. Infection. The most common cause of delayed healing in chronic wounds is infection.
    2. Osteomyelitis.
    3. Tissue Necrosis and Gangrene.
    4. Periwound Dermatitis.
    5. Edema and Periwound Edema.
    6. Hematomas.
    7. Dehiscence.

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Asked: 6 years agoIn: Pathology

What are the factors that affect the wound healing process?

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  1. Dr Md shahriar kabir B H M S; MPH
    Dr Md shahriar kabir B H M S; MPH Enlightened dr.basuriwala
    Added an answer about 3 years ago

    Wound healing can be affected by intrinsic, extrinsic, and iatrogenic factors. Intrinsic factors are related to the overall state of health of the patient, such as age, body type, chronic disease, immunosuppression, nutritional status, and hormonal levels. Extrinsic factors are related to the externRead more

    Wound healing can be affected by intrinsic, extrinsic, and iatrogenic factors. Intrinsic factors are related to the overall state of health of the patient, such as age, body type, chronic disease, immunosuppression, nutritional status, and hormonal levels. Extrinsic factors are related to the external environment and conditions of the wound, such as dehydration, blood supply, sepsis, and occlusive dressing. Iatrogenic factors are related to the medical interventions and treatments that can influence wound healing, such as medications, radiation therapy, and surgery. These factors can delay or complicate the wound-healing process by affecting cellular functions, immune response, and tissue repair.

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